Sterile pharmaceutical products are prepared by sterile filtering and then aseptically filling solutions into glass vials. The compounding area is equipped with an Enguard isolator to allow potent and cytotoxic APIs to be safely handled. After filling, vials can undergo lyophilization if desired. Batch sizes can range from a few hundred vials to up to 4,000 vials or 40 L of bulk solution (whichever is less), depending on the fill volume of the product. Differential air pressures, along with other measures, including cleaning verification and dedicated product contact equipment components, are used to prevent cross-contamination.  Because our fillers use peristaltic pumps and a single fill needle, line losses are low compared to larger operations.