UI Pharmaceuticals has been preparing clinical supplies for blinded clinical trials for over 40 years. Let us help you successfully blind your comparator drugs.


Comparator Products

Lyophilization Cycle Development


Clinical Supply Manufacturing


Small Scale Commercial Manufacturing


Analytical Method Development and Validation


Routine Quality Control Analysis


Stability Assessment


Formulation Development


Comparator Products


Powder in a Bottle


Preformulation Studies


Active Pharmaceutical Ingredient (API) and Excipient Release Testing


QP Release Services


Comparator DrugProgramming Tablet Coating Processing Parameters

The University of Iowa Pharmaceuticals’ (UIP) Solid Dosage Form Products Group has the capability to prepare comparator drugs for clinical trials via a variety of means, depending on the characteristics of the dosage forms.


Techniques that can be used include:

  • Placing products into empty capsule shells and overfilling with inert powders
  • Milling commercially available products and filling the resultant powder into empty capsule shells
  • Removing ink logos from commercially available tablets or capsules
  • Film coating over existing brand marking
  • Production of look-a-like placebo dosage forms




Filling Empty Capsule Shells into Rings

Once your product, appropriate comparator drugs, and/or placebos have been rendered identical in appearance, UIP can sort them by weight to ensure the weight of every dosage unit is within the confirmed weight range. UIP can package finished products into bottles or bulk containers and apply labeling. Patient kits can be assembled and supplies can be shipped straight to clinical sites.


To learn more about our ability prepare comparator drugs for clinical trials, or our how we manufacture and package comparator drugs and other products, please Contact Us.