With the installation of a new Lyotherm 2 and Lyostat 2, UIP has significantly enhanced its lyophilization cycle development capabilities. The Lyotherm 2 provides UIP with an integrated Differential Thermal Analyser (DTA) and electrical impedance (Zsinφ) capability in a single instrument. This allows measurement of glass transition (Tg'), eutectic (Teu) and melting (Tm) temperatures relevant to freeze-drying formulations. The Lyostat 2 is a fully integrated freeze-drying microscope that enables critical events, such as collapse and melting, to be observed in situ, as well as characteristics such as skin or crust formation to be observed and identified. The coupled Lyostat 2 and Lyotherm 2 units provide valuable information for both formulation and cycle development processes. With UIP's in-house expertise in lyophilization, the purchase of this system will allow quicker and more efficient development of lyophilization cycles.