UI Pharmaceuticals Provides Tableting and Encapsulation Services
University of Iowa Pharmaceuticals (UIP) offers pharmaceutical product development, manufacturing, and testing services for tablet and capsule products. Because UIP is registered with the FDA as a Drug Product Manufacturing and Testing Facility, we are able to produce and test products for both clinical studies and commercial sale. Let us help you meet your tablet and/or capsule manufacturing and testing needs.
- Each manufacturing room has its own gowning/entry way that opens from a central staging area.
- Differential air pressures and single pass air, along with other measures including cleaning verification, are used to prevent cross-contamination.
- Special protective suites, wireless intercoms and video feeds, and supplied air respirators are used to protect employees from exposure to potent/toxic materials.
- The area is supported with a clean, dry compressed air system and a hot loop USP Purified Water system.
- All incoming air is HEPA filtered and humidity controlled and exhausted air is double HEPA filtered.
- UIP can process controlled substances schedules I-V and most potent/cytotoxic compounds.
Tablet and capsule dosage forms can be produced using a variety of processes including roller compaction, wet granulation, and simple blending. Batch sizes can range from a few hundred to hundreds of thousands of dosage units, depending on the dosage form unit weight and formulation blend density.
Processing techniques available to prepare products include:
- Screening, Milling or Micronizing
- Roller Compaction
- Low or High Shear Wet Granulation
- Fluid Bed Granulation or Coating
- Fluid Bed or Conventional Drying
- Holt Melt Capsule Filling
- Tablet or Capsule Pan Coating
- Low or High Shear Blending
- Capsule Banding
Once dosage forms are produced, UIP can sort them by weight to ensure the weight of every dosage unit is within the specified weight range. UIP has the ability to package finished products into bottles or bulk containers and apply labeling as desired. Clinical kits can be assembled and materials shipped directly to clinical sites. UIP is fully capable of preparing comparator products via a variety of means.
For more information about our solid dose pharmaceutical manufacturing and packaging capabilities please, Contact Us or view our Full Equipment List here.