The University of Iowa

UI Pharmaceuticals Offers Liquid and Semisolid Small Scale Commercial Manufacturing and Testing Services

Although the bulk of UI Pharmaceuticals projects over the years have supported clinical studies, small scale pharmaceutical manufacturing and testing of commercial products has been performed for most of the last 20 years.  A non-sterile gel drug product is currently being produced and tested at our facility and being sold in the US and several other countries around the world.

Filled tubes moving on conveyor belt
UI Pharmaceuticals is registered as a drug product manufacturing and testing facility with FDA and a non-sterile gel is being produced and tested at our facility and sold commercially.  This product is produced and tested under strict master batch record, standard operating procedure, and cGMP controls.  Batch records and testing records are completely audited after manufacturing and testing by the Quality Assurance Group. 

UIP has three manufacturing suites: two suites are dedicated to the handling of potent/cytotoxic compounds and one suite is divided into four separate manufacturing rooms and is designed for handling less potent/toxic materials.

Each manufacturing room has its own gowning/entry way that opens from a central staging area.

Differential air pressures and single pass air, along with other measures including cleaning verification, are used to prevent cross-contamination. 

Special protective suites, wireless intercoms and video feeds, and supplied air respirators are used to protect employees from exposure to potent/toxic materials.  

The area is supported with a clean, dry compressed air system and a hot loop USP Purified Water system. 

All incoming air is HEPA filtered and humidity controlled and exhausted air is double HEPA filtered.

6 gm machine

UIP can process controlled substances schedules I-V and most potent/cytotoxic compounds.

Processing equipment includes a Tonazi tube filler and sealer, various propeller style overhead mixers, stainless steel tanks, and Hobart planetary mixers with counter sweeps. 

Finished products can be filled into bottles, jars, or tubes or in bulk. 

For more information about our non-sterile liquids, creams, gels, and ointments manufacturing and packaging capabilities please Contact Us.  View our Full Equipment List here.