In addition to producing and testing sterile products and solid dosage forms, University of Iowa Pharmaceuticals (UIP) has non-sterile liquid and semisolid manufacturing and testing capabilities for liquids, creams, gels, and ointments, as well as less common dosage forms such as suppositories. 

UIP has three manufacturing suites: two suites are dedicated to the handling of potent/cytotoxic compounds and one suite is divided into four separate manufacturing rooms and is designed for handling less potent/toxic materials.

Each manufacturing room has its own gowning/entry way that opens from a central staging area.

Differential air pressures and single pass air, along with other measures including cleaning verification, are used to prevent cross-contamination. 

Special protective suites, wireless intercoms and video feeds, and supplied air respirators are used to protect employees from exposure to potent/toxic materials.  

The manufacturing area is supported with a clean, dry compressed air system and a hot loop USP Purified Water system. 

All incoming air is HEPA filtered and humidity controlled and exhausted air is double HEPA filtered.

UIP can process controlled substances schedules I-V and most potent/cytotoxic compounds.

• Processing equipment includes a Tonazi tube filler and sealer, various overhead mixers, stainless steel tanks, and Hobart mixers equipped with counter-sweeps. 
• Finished products can be filled into bottles, jars, or tubes or in bulk. 
• Finished containers can be labeled.  If desired, patient kits can be assembled and materials shipped directly to clinical sites for smaller trials. 

For more information about our non-sterile liquids, creams, gels, and ointments manufacturing and packaging capabilities please Contact Us.  View our Full Equipment List here.