University of Iowa

UI Pharmaceuticals Provides a Full Range of Non-Sterile Processing Capabilities

University of Iowa Pharmaceuticals (UIP) offers pharmaceutical product development, manufacturing, and testing services for tablets, capsules, and non-sterile powder, semisolid, and liquid products.  Because UIP is registered with the FDA as a Drug Product Manufacturing and Testing Facility, we are able to produce and test products intended for both clinical studies and commercial sale.  Let us help you meet your non-sterile product manufacturing and testing needs.

Steve at a solide dosage mechine
The University of Iowa Pharmaceuticals’ (UIP) Non-sterile Products area has four suites: one suite is dedicated to tablet and capsule coating, two suites are dedicated to the handling of potent/cytotoxic compounds, and one suite is divided into four separate manufacturing rooms and is designed for handling less potent/toxic materials.
  • Each Non-Sterile Products manufacturing room has its own gowning/entry way that opens from a central staging area.
  • Differential air pressures and single pass air, along with other measures including cleaning verification, are used to prevent cross-contamination. 
  • Special protective suites, wireless intercoms and video screens, and supplied air respirators are used to protect employees from exposure to potent/toxic materials.  
  • The Non-Sterile Products area is supported with a clean, dry compressed air system and a hot loop USP Purified Water system. 
  • All incoming air is HEPA filtered and humidity controlled and exhausted air is double HEPA filtered.
  • We are able to handle controlled substances schedules I-V and most potent/cytotoxic materials.

tablet press

 

The Non-Sterile Products Group offers a range of services including:

The Non-Sterile Products Group has the capability to produce tablet and capsule dosage forms using a variety of processes. Batch sizes can range from a few hundred to hundreds of thousands of dosage units, depending on the dosage form unit weight and formulation blend density.  Our largest blender will hold approximately 100 kg of product (depending on density).  Non-sterile powders (up to approximately 100 kg), semisolids (up to approximately 100 kg), and liquids (up to 800 L) can also be prepared.

For more information about our non-sterile pharmaceutical manufacturing and packaging capabilities please, Contact Us or view our Full Equipment List here.